ACCELERATING THE CURE
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EARLY VACCINES
Developing novel vaccines for solid metastatic cancers using B lymphocytes
WHAT ARE VACCINES FOR CANCER?
Vaccines are medicines that train the immune system to help the body fight disease. In oncology, there are vaccines to prevent cancer and vaccines to treat cancer.
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Vaccines that treat an existing cancer are also called treatment vaccines, and are a type of cancer treatment called Immunotherapy.
WHAT ARE B LYMPHOCYTES?
B lymphocytes are key players of the adaptive immune response that is responsible for humoral immunity.
B-cell production in humans is a lifelong process and their development is from hematopoietic stem cells.
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ADVANCED CELL THERAPY
Bioengineering patient cells and using them to fight the patient's cancer
BIOENGINEERING APPROACHES
Advanced cell therapy approaches leverage bioengineering approaches, including the design of biomaterials, delivery strategies and nanotechnology solutions, for the realisation of individualised cancer treatments. Developments in precision cancer immunotherapy will increasingly rely on the adoption of bioengineering principles.
ADVANCED CELL IMMUNOTHERAPY
Cancer immunotherapies harness and boost the body's immune system to target and kill tumour cells. This includes bioengineered T cells and vaccines that trigger antigen-specific immune responses in tumours.
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We support such programs that aim to Improve patient response rates and the safety of cancer immunotherapies.
TUMOUR MICROENVIRONMENT
Every cancer is surrounded by a small environment - or microenvironment - of normal cells, molecules and blood vessels that surround a feed the unwanted tumour cells. A tumour can change its microenvironment, and the microenvironment can affect how a tumor grows and spreads.
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Understanding the tumour microenvironment can help us overcome it to inhibit tumour growth.
GENETICALLY ENGINEERED T CELLS
T cells in the immune system protect the human body from infection by pathogens. They play central roles in cell-mediated adaptive immunity.
By genetically engineering T cells of a patient, you can boost their antitumor efficacy that effectively inhibits immune checkpoints and expands adaptive immunity.
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We support programs that aim to improve the performance of these T cells in fighting cancers.
3
OUTSMARTING CANCER CELLS
Overcoming the Microenvironment of tumours using genetically engineered T-Cells
